The final laminar position and subtype of cortical projection neurons is highly dependent on the time progenitors undergo final mitosis and exit the cell cycle (Mc Connell and Kaznowski 1991; Takahashi et al. Throughout corticogenesis, progenitor cell divisions generate cells that must decide whether to reenter the cell cycle or exit the cell cycle and differentiate into neurons with defined laminar fates. 2001), lack eyes and nasal structures, and die soon after birth (Hogan et al. Embryonic or postnatal brains were harvested at the times specified after tamoxifen treatment. All the experimental procedures were performed in accordance with institutional guidelines and UK Home Office regulations.
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